Memoria espacial y cuerpos mamilares

L. J. Santín; S. Rubio; J. M. Cimadevilla; A. Begega; J. L. Arias

doi:10.24310/espsiescpsi.vi1.13422

Authors

L. J. Santín Laboratorio de Neurociencias, Facultad de Psicología, Universidad de Oviedo. Spain
S. Rubio Laboratorio de Neurociencias, Facultad de Psicología, Universidad de Oviedo. Spain
J. M. Cimadevilla Laboratorio de Neurociencias, Facultad de Psicología, Universidad de Oviedo. Spain
A. Begega Laboratorio de Neurociencias, Facultad de Psicología, Universidad de Oviedo. Spain
J. L. Arias Laboratorio de Neurociencias. Facultad de Psicología. Universidad de Oviedo. Spain

DOI:

https://doi.org/10.24310/espsiescpsi.vi1.13422

Keywords:

Spatial memory, mamillary bodies, Korsakoff 's syndrome

Abstract

This review critically analyses the implication of the mamillary bodies (MB) in the spatial learning and memory processes. It shows the current controversies in this field and its clinical implications. The experimental works about this subject shown that MB is one of the diencephalic structures that form part of the cerebral circuitry or circuitries underlying memory processes. This review is focused on results from clinical and experimental investigations, that shown the involvement of MB on learning and memory tasks. lt is mainly analysed the behavioral tasks that involve spatial information.

Downloads

Metrics

Visualizaciones del PDF

290

|

Wikipedia

1

References

Aggleton, J. P. y Shagal, A. (1993). The contribution of the anterior thalamic nuclei to anterograde amnesia. Neuropsychologia, 31, 1001-1019.

Aggleton, J. P. , Hunt, P. R. y Shaw, C. (1990). The effects of mammillary body and combined amigdalar-fornix lesions on test of delayed non-matching to sample in rat. Behavioral Brain Research, 40, 145-157.

Aggleton, J. P., Keith, A.B. y Shagal, A. (1991). Both fornix and anterior thalamic, but not mammillary lesions disrupt delayed non-matching to position memory in rats. Behavioral Brain Research, 44, 151-161.

Aggleton, J. P., Neave, N.; Nagle, S. y Hunt, P. R. (1995). A comparison of the effects of anterior thalamic, mammillary body and fornix lesions on reinforced spacial alternation. Behavioral Brain Research, 68, 91-101.

Albert, M. S., Butters, N. y Levin, J. (1979). Temporal gradients in the retrograde amnesia of patients with alcoholic Korsakoff’s disease. Archives of Neurology, 36, 211-216.

Allen, G. V. y Hopkins, D.A. (1988). Mammillary body in the rat: a citoarchitectonic, Golgi and ultrastructural study. Journal of Comparative Neurology, 275, 39-64.

Becker, J. T., Walker, J. A. y Olton, D. S. (1980). Neuroanatomical bases of spacial memory. Brain Research, 200, 307-321.

Beracochea, D. J. y Jaffard, R. (1987). lmpairment of spontaneous alternation behavior in sequential test procedures following mammillary body lesions in mice: Evidence for time-dependent interference-related memory deficits. Behavioral Neuroscience, 101, 187-197.

Beracochea, D. J. y Jaffard, R. (1990). Effects of ibotenic lesions of mammillary bodies on spontaneous and rewarded spacial alternation in mice. Journal of Cognitive Neuroscience, 2, 133-140.

Beracochea, D. J. y Jaffard, R. (1995). The effects of mammillary body lesions on delayed matching and delayed non-matching to place tasks in mice. Behavioral Brain Research, 68, 45-52.

Beracochea, D. J. y Krazem, A. (1991). Effects of mammillary body and mediodorsal thalamic lesions on elevated plus maze exploration. Neuroreport, 2, 793-796.

Beracochea, D. J., Alaoui-Bouarraqui, F. y Jaffard, R. (1989). lmpairment of memory in a delayed non-matching to place task following mammillary body lesions in mice. Behavioral Brain Research, 34, 147-154.

Bezing, W. C. y Squire, L. R. (1989). Preserved learning and memory in amnesia: intact adaptation level effects and learning of estereoscopic depth. Behavioral Neuroscience, 103, 538-547.

Bruin, J. P. C., Sanchez-Santez, F., Heinsbroek, R. P. W., Donker, A. y Postmes, P.(1994). A behavioural analysis of rats with damage to the medial prefrontal cortex using the morris water maze: evidence for behavioural flexibility, but not for impaired spacial navigation. Brain Research, 625, 323-333.

Bunge, M. y Ardila, R. (1988). Filosofía de la psicología. Ariel. 1ª ed. Barcelona.

Carpenter, M. B. (1994). Neuroanatomía. Fundamentos. Buenos Aires: Ed. Panamericana.

Cohen, J. D., Perlstein, W. M., Braver, T. S., Nystrom, L.E., Noll, D. C., Jonides, J. y Smith, E. E. (1997). Temporal dynamics of brain activation during a working memory task. Nature, 386, 604-607.

Condé, F., Maire-Lepoivre, E., Audinat, E. y Crépel, F. (1995). Afferent connections to the medial prefrontal cortex of the rat: II. Cortical and sub-cortical afferents. Journal of Comparative Neurology, 325, 567-593.

Courtney, S. M., Ungerleider, L. G., Katrina, K. y Haxby, J. V. (1997). Transiet and sustained activity in a distributed neural system for human working memory. Nature, 386, 608-611.

Craik, F. I. M. (1991): Memory functions in normal aging. En Yanagihara, T., Petersen R. C. Memory disorders: research and clinical practice. New York: Dekker, pp. 347-367.

DSM-IV. Manual diagnóstico y estadístico de los trastornos mentales American Psychiatric Association (1995). Barcelona: Masson, S.A.

Dusoir, H., Kapur,N., Byrnes, D. P., McKinstry, S. y Hoare, R. D. (1990). The role of Diencephalic pathology in human memory disorder. Brain, 113,1695-1706.

Frick, K. M., Baxter, M.G., Markowska, A. L., Olton, D. S. y Price, D.L. (1995). Aged-related spacial reference and working memory deficits assessed in the water maze. Neurobiology of Aging, 16, 149-160.

Funahashi, S., Bruce, C. J., Goldman-Rakic, P.S. (1993). Dorsolateral prefrontal lesions and oculomotor delayed-response performance: evidence for mnemonic «scotomas». Journal of Neuroscience, 13, 1479-1497.

Fuster, J. M. (1994). Memory in the cerebral cortex. The MIT Press, Cambridge, MA.

Goldman-Rakic, P. (1997). Space and time in the mental universe. Nature, 386, 559-560.

Gonzalo-Ruiz, A., Alonso, A., Sanz, J. M. y Llinás, R. R. (1992). Afferent projections to the mammillary complex of the rat, with special reference to those from surrounding hypothalamic regions. Journal of Comparative Neurology, 321, 277-299.

Granon, S. y Poucec, B. (1995). Medial prefrontal lesions in the rat and spacial navigation: Evidence for impaired planning. Behavioral Neuroscience, 109, 474-484.

Granon, S., Vidal, C., Thinus-Blanc, C., Changeux, J. P., y Poucec, B. (1994). Working memory, response selection and effortful processing in rats with medial prefrontal lesions. Behavioral Neuroscience, 108, 883-891.

Gross, C. G. y Graziano, M. S. A. (1995). Multiple representations of space in the brain. The Neuroscientist, 1, 43-50.

Harper, D. N., Dalrymple-Alford, J. C. y McLean, A. P. (1993). The effect of medial septal and mammillary body lesions on the serial position curve in rats. Psychobiology, 21, 130-138.

Harper, D. N., McLean, A. P. y Dalrymple-Alford, J. C. (1994). Forgetting in rats following medial septum or mammillary body damage. Behavioral Neuroscience, 108, 691-702.

Hayakawa, T. y Zyo, K. (1989). Retrograde double-labeling study of the mammillothalamic and the mammillothegmental projections in the rat. Journal of Comparative Neurology, 284,1-11.

Hebb, D. O. (1949). The organization of behavior. Wiley, New York.

Héroux, D. N. y Butterworth, R.F. (1992). Animal models of the Wernicke-Korsakoff syndrome. En: A. Boulton, G., Backe, y R. Butterworth. Animal Models of Neurological Disease Il. The Human Press.

Holmes E. J., Butters, N., Jacobson, S. y Stein, B.M. (1983b). An examination of the effects of mammillary body lesions on reversal learning sets in monkeys. Physiology Psychology, 11, 159-165.

Holmes, E. J., Jacobson, S., Scein, B.M. y Butters, N. (1983a). Ablations of the mamillary nuclei in monkeys: Effects on postoperative memory. Experimental Neurology, 81, 97-113.

Jarrad, L. E., Okaichi, H., Steward, O. y Goldschmidt, R. (1984). On the role of hippocampalconnections in the performance of the place and cue tasks: Comparisons with damage to hippocampus. Behavioral Neuroscience, 98, 946-954.

Kolb, B. y Whishaw, I. Q (1986). Fundamentos de neuropsicología humana. Labor. Barcelona.

Kopelman, M. D. (1989). Remote and autobiographical memory, temporal context memory and frontal atrophy in Korsakoff and Alzheimer patients. Neuropsychologia, 27 , 437-460

Kopelman, M. D. (1995). The Korsakoff syndrome. British journal of Psychology 166, 154-173.

Krazem, A.; Beracochea, D. y Jaffard, R. (1995). Effects of mammillary bodies and mediodorsal thalamic lesions on the acquisicion and retention of a learning set in mice: Paradoxical effect of the intersession interval. Behavioral Brain Research, 67, 51-58.

Lisk, R. O. (1966). Increased sexual behavior in the male rat following lesions in the mammillary region. Journal of Experimental Zoology, 161, 129-136.

Mair, R. G. y Lacourse, D.M. (1992). Radio frecuency lesions of the thalamus produce delayed non-matching to sample impairments comparable to pyrithiamine induced encephalopathy in rats. Behavioral Neuroscience, 106, 634-645.

Mair, W. G. P., Warrington, E.K. y Weiskrantz, L. (1979). Memory disorder in Korsakoff psychosis. A neuropathological and neuropsychological investigation of two cases. Brain, 102, 749-783.

Marslen-Wilson, W. D. y Teuber, H. L. (1975). Memory for remote events in anterograde amnesia: recognition of public figures from news photographs. Neuropsychologia, 13, 353- 364.

Mayes, A. R. (1995). Memory and amnesia. Behavioral Brain Research, 66, 29-36. ·

Morris, R. G. M. (1984). Developments of a water-maze procedure for studying spatial learning in the rat. Journal of Neuroscience Methods, 11, 47-60.

O’keefe, J. y Nadel, L. (1978). The hippocampus as a cognitive map. Clarendon Press. Oxford.

Olton, D. S. (1987). The radial arm maze as a tool in behavioral pharmacology. Physiology and Behavior, 40, 793-797.

Olton, D. S. y Samuelson, R.J. (1976). Remembrance of places passed: spatial memory in rats. Journal of Experimental Psychology, 2, 97-116.

Papez, J. W. (1937). A proposed mechanism of emotion. Archives of Neurology Psychiatry, 38, 725-743.

Parkinson, J. K., Murray, E. y Mishkin, M. (1982). A selective mnemonic role for the hippocampus in monkeys: memory for the location of objects. Journal of Neuroscience, 8, 41-59.

Petersen, R. O., Smith, G., Kokmen, E.; Iunik, R. J. y Tangalos, E.G. (1992). Memory function in normal aging. Neurology, 42, 396-401.

Rawlins, J. N. P., Feldon, J., Tonkiss, J. y Coffey, P. J. (1989). The role of subicular outputs in the development of the partial reinforcement extinction effect. Experimental Brain Research, 77, 153-160.

Rosenzweig, M. R., Krech, D., Bennett, E.L. y Diamond, M.C. (1962). Effects of environmental complexity and training on brain chemistry and anatomy: a replication and extension. Journal of Comparative Physiology, 55, 429-437.

Ruiz-Vargas, J. M. (1991): Sistemas y Medidas de Memoria. En: Psicología de la Memoria. Alianza Editorial, Madrid. pp. 57-84.

Saravis, S., Sziklas, V. y Petrides, M. (1990). Memory for places and the region of the mammillary bodies in rats. European Journal of Neuroscience, 2, 556-564.

Shibata, H. (1993). Efferent projections from the anterior thalamic nuclei to the cingulate cortex in the rat. Journal of Comparative Neurology, 330, 533-542.

Shimamura, A. P. (1986). Priming effects in amnesia: evidence for a dissociable memory function. Quaterly journal of Experimental Psychology 133, 556-570.

Smith, M. L. y Milner, B. A. (1981). The role of the right hippocampus in the recall of spatial location. Behavioral Brain Research, 32, 265-277.

Squire, L. R. y Zola-Morgan, S. (1991). The medial tempora lobe memory system. Science, 253, 1380-1386.

Squire, L. R., Amaral, D. G. y Pres, G. A. (1990). Magnetic resonance imaging of the hippocampal formation and mammillary nuclei distinguish medial temporal lobe and diencephalic amnesia. Journal of Neuroscience, 10, 3106-3117.

Squire, L. R., Knowlton, B. y Musen, G. (1993). The structure and organization of memory. Annual Review of Psychology, 44, 453-495.

Sutherland, R. J. y Rodriguez, A. J. (1989). The role of the fornix fimbria and some related subcortical structures in place learning and memory. Behavioral Brain Research, 32, 265-277.

Sziklas, V. y Petrides, M. (1993). Memory impairments following lesions to the mammillary region of the rat. European Journal of Neuroscience, 5, 525-540.

Sziklas, V., Petrides, M. y Leri, F. (1996). The effects of lesions to the mammillary region and the hippocampus on conditional associative learning by rats. European Journal of Neuroscience, 8, 106-115.

Tanaka, Y., Miyazawa, Y., Akaoka, F. y Yamada, T. (1997). Amnesia following damage to the mammillary bodies. Neurology, 48, 160-165.

Tarpy, R. M. (1982): Memoria Animal. En: Aprendizaje y Motivación Animal. Ed. Debate, Madrid. pp. 261-287.

Thompson, R., Langer, S. K. y Rich, I. (1964). Lesions of the limbic system and short-term memory in albino rats. Brain, 87, 537-542.

Tonkiss, J. y Rawlins, J. N. P. (1992). Mammillary body lesions and restricted subicular output lesions produce long-lasting DRL performance impairments in rats. Experimental Brain Research, 90, 572-582.

Vanderwolf, C. H. y Cain, O. P. (1994). The behavioral neurobiology of learning and memory: a conceptual reorientation. Brain Research Review, 19, 264-297.

Zola-Morgan, S., y Squire, L. R. (1993). Neuroanatomy of memory. Annual Review of Neuroscience, 16, 547-563.

Zola-Morgan, S.; Squire, L. R. y Amaral, D.G. (1989). Lesions of the hippocampal formation but not lesions of the fornix or the mammillary nuclei produce long-lasting memory impairment in monkeys. Journal of Neuroscience, 9, 898-913.