Lung Cancer Genomics

Authors

  • Macarena Arroyo Varela Spain
  • Rocío Bautista Moreno Spain
  • M. Gonzalo Claros Díaz Spain
  • José Luis De la Cruz Ríos Spain

Keywords:

cancer, metastatic, lung

Abstract

In simplified terms, cancer consists of an uncontrolled proliferation of cells because proliferative signals are maintained and antiproliferative ones, such as cell death and immune response, are evaded. These cells also have angiogenic and metastatic capabilities, which confer the characteristic malignancy to cancer. When uncontrolled growth occurs in some type of cell in the respiratory system, we have lung cancer, which is considered a malignant tumor that invades neighboring structures and forms metastases in other tissues by spreading through the blood or lymph. In turn, the lung is a destination for metastases from other cancers unrelated to the respiratory system

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References

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Lindeman NI et al. Molecular testing guideline for selection of lung cancer patients for EGFR and ALK tyrosine kinase inhibitors: guideline from the College of American Pathologists, International Association for the Study of Lung Cancer, and Association for Molecular Pathology. J Mol Diagn 15(4): 415-53, 2013.

You M et al. Fine mapping of chromosome 6q23-25 region in familial lung cancer families reveals RGS17 as a likely

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Bettegowda C et al. Detection of circulating tumor DNA in early- and late-stage human malignancies. Sci Transl Med 6(224): 224ra24, 2014

Published

2015-09-24

How to Cite

Arroyo Varela , M., Bautista Moreno , R., Claros Díaz, M. G., & De la Cruz Ríos, J. L. (2015). Lung Cancer Genomics. Encuentros En La Biología, 9(155), 17–21. Retrieved from https://revistas.uma.es/index.php/enbio/article/view/18007

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Artículos