The ‘RNA interference’ mirrors the path to the Nobel

Authors

  • M. Gonzalo Claros

Keywords:

RNA interference, nobel, RNA, double-stranded

Abstract

On October 2nd, it was announced that the 2006 Nobel Prize in Physiology and Medicine was awarded to Andrew Z. Fire and Craig C. Mello for their discoveries about RNA interference and gene silencing by double-stranded RNA. Although in 1990, Napoli, Lemieux, and Jorgensen discovered in petunias the phenomenon they called co-suppression, which consists of gene silencing by homologous sequences, the key to discovering the bases of this process was published in 1998 by Andrew Fire and Craig Mello in the journal Nature: they observed that the phenomenon not only occurs in plants, but that the injection of double-stranded RNA in C. elegans triggers a biochemical machinery that leads to a sequence-specific gene silencing

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Published

2006-11-20

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How to Cite

The ‘RNA interference’ mirrors the path to the Nobel. (2006). Encuentros En La Biología, 113, 6-7. https://revistas.uma.es/index.php/enbio/article/view/18618