Applications of New Sequencing Technologies

Authors

  • Rosario Carmona Muñoz

Keywords:

nuevas tecnologías de secuenciación, aplicattions, nucleotide

Abstract

In issue 128 of Encounters in Biology, a general overview of the three generations of sequencing (NGS, new generation sequencing) was published. These technologies are evolving at a rapid pace, and since that article, it is worth noting, for example, the considerable advancement of Illumina technology, with its HiSeq 2500/1500 system, capable of generating up to 600 Gigabases per reaction.

Also noteworthy is the development of a novel sequencing system: Ion Torrent, in which nucleotides are not detected by fluorescence or light emission, but by the change in pH as a result of the release of a proton following the incorporation of the nucleotide. 

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References

Bautista R. Las tres generaciones de la secuenciación. Encuentros en Biología. Vol. 3, 128: 27-28 (2010).

Robertson G, Hirst M, Bainbridge M, Bilenky M, Zhao Y, Zeng T, Euskirchen G, Bernier B, Varhol R, Delaney A et al. Genome-wide profiles of STAT1 DNA association using chromatin immunoprecipitation and massively parallel sequencing. Nat. Methods 4: 651–657 (2007).

Zhang Y, Jeltsch A. The aplication of next generation sequencing in DNA methylation analysis. Genes 1: 85- 101 (2010).

Egan AN, Schlueter J, Spooner DM. Applications of next-generation sequencing in plant biology. American Journal of Botany 99: 175-185 (2012).

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Published

2012-07-20

Dimensions

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How to Cite

Applications of New Sequencing Technologies. (2012). Encuentros En La Biología, 5(138-139), 41-42. https://revistas.uma.es/index.php/enbio/article/view/18427